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Research & Clinical Trials




Clinical Trials in Neuropathy and Neuromuscular Disease



Clinical Trials of SB-509 in Subjects With Diabetic Neuropathy



Do You Have Diabetes and Prickling, Tingling, Numbness, or Pain in Your Feet?



If so, you may be eligible to participate in a RESEARCH STUDY testing an experimental drug to treat diabetic peripheral neuropathy.

To be eligible, you must:
  • Be 18 years of age or older
  • Have either Type 1 or Type 2 diabetes
  • Have met diagnostic criteria for diabetic peripheral neuropathy
  • Not be pregnant or intend to become pregnant during the study
Study participant will be assigned to take experimental drugs or placebo (no active treatment) that are injected every 2 months for 3 months. The study lasts for 1 year. This drug has not been approved by the Food & Drug Administration (FDA). There is no cost for your participation. If you qualify during the screening visits, there will be compensation to defer travel costs, during the remainder of the study.

If you are interested, or know of a friend or relative who might be interested in participating, please call the following:

Darleen Vecchio


212 342-3026

Thomas Brannagan, MD


Diabetic Neuropathy Research Center
Columbia Univeristy Medical College
The Neurological Institute
710 West 168th Street
NY, NY 10032

For more information please click here.



A Multicenter, Single-Blind, Randomized Study Comparing Thymectomy to No Thymectomy in Non-Thymomatous Myasthenia Gravis (MG) Patients Receiving Prednisone



STATUS: Enrolling





Basic Science of Nerve and Muscle



The role of RAGE in peripheral nervous system degeneration and regeneration.



This series of basic science studies explore the role of the Receptor for Advanced Glycosolation End products (RAGE) on nerve degeneration and recovery following traumatic nerve injury.

STATUS: Ongoing research; no human component at present.



FOR MORE INFORMATION: See "Rong LL, Gooch C, Szabolcs M, Herold KC, Hays AP, Yan SF, Du Yan SS, and Schmidt AM: RAGE & the Nervous System: Striking A Fine Balance Between Injury & Repair. Restorative Neurology and Neuroscience. 2006;23:355-65.



Projects In Development:



NOTE: We are actively seeking funding for these studies, which remain in development and are not yet launched or enrolling.

If you are an individual, organization or company and may be interested in underwriting a project, please contact Thomas Brannagan, MD at 212-305-0405.


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©2006-2008 The Neurological Institute of New York • At Columbia University Medical Center
The Columbia Neuropathy Research Center. 710 W 168th St, New York, NY 10032. Phone: 212-305-0405
Updated June 9, 2009
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